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17 The excess accumulation of hydrogen peroxide is damaging to macromolecules such as DNA, protein, and lipids, leading to organelle damage (especially mitochondria 18 ), cellular damage, tissue damage, and ultimately organ damage

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Two‑sided Student’s t -test or two‑sided Welch’s t test was utilized to compare two groups, two‑sided Mann–Whitney U test was used to compare two groups as the data were not normally distributed