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Moreover, the NF-κB pathway shares common upstream activators with the MAPK and PI3K/Akt pathways, and there exists a cross-regulation among these pathways, collectively influencing biological processes such as inflammation, cell survival, proliferation, and apoptosis ( 2.3.2 Marine-derived products in NF-κB-related pathways regulation Marine natural products offer multiple protective effects in inflammatory lung injury by targeting NF-κB and related signaling pathways

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These modifications change the peptide’s interaction with igf binding proteins