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Collectively, these findings highlight the synergistic harmful impact of alcohol and HBV on liver disease progression, consistent with epidemiological data showing higher HBV marker levels and worse liver outcomes, including cirrhosis and HCC, in alcoholic individuals with HBV infection

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Recent data have demonstrated that nitrated tyrosine residues, as well as acetaminophen adducts, occur in the necrotic cells following toxic doses of acetaminophen