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The model output ranged from 0 to 1, and a cutoff of ≥0.5 was used to classify the predictions into 0 (no BBB permeation) and 1 (BBB permeation)

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demonstrated that the AEDG peptide induced telomerase catalytic subunit (hTERT) expression in human fetal fibroblast cultures, resulting in measurable telomerase activity and an average telomere elongation of 33.3% (3)