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For superoxide anion, the main ROS, a first line of defense is represented by the enzyme superoxide dismutase, localized in the mitochondrial matrix

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Blood and Stool Tests Blood tests can show: Anaemia (low red blood cell count), often from blood loss or chronic inflammation Raised inflammation markers, such as C-reactive protein (CRP) Low levels of iron, vitamin B12, vitamin D, or other nutrients Stool tests can: Rule out infections such as Clostridioides difficile or parasitic infections that can mimic or worsen IBD Measure faecal calprotectin, a protein released into stool when the bowel is inflamed